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Newly developed drug helps extend the lives of lung cancer patients in trial

Related: ‘Trailblazing’ NHS pilot combines AI and robotics to spot lung cancer faster
  • A new dual-action drug, Ivonescimab, combined with chemotherapy, has shown promise in extending the lives of patients with advanced squamous non-small cell lung cancer.
  • The investigational treatment works by disabling the ‘off’ switch used by tumours to evade the immune system and targeting a protein crucial for tumour growth.
  • A trial involving 532 patients in China found that those receiving Ivonescimab and chemotherapy lived an average of 28 months, a 15 per cent increase compared to a control group.
  • Experts have described these findings as a “promising step forward” for this hard-to-treat lung cancer, though further investigation is required.
  • While side effects were more common with the new drug, the rate of patients discontinuing treatment due to side effects remained similar across both treatment groups.
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