In his resignation letter, Mr Streeting accused Sir Keir of creating a ‘vacuum’ where the country needed a ‘vision’ and urged him to ‘listen to your colleagues’.
Mr Streeting is widely expected to mount a leadership challenge against Sir Keir Starmer.
Downing Street has confirmed that Sir Keir Starmer has vowed to ‘fight on’ despite suggestions of an imminent challenge to his leadership.
Mr Streeting’s letter detailed his achievements as Health Secretary, including surpassing waiting time targets and improving NHS performance, but concluded it would be ‘dishonourable and unprincipled’ to remain in post.