Gut health has become something of a wellness phrase, but it’s not just a passing trend. The gut actually refers to a complex system of organs – from the mouth through to the large intestine – that collectively house trillions of microbes. Among them are probiotics, which help keep this internal ecosystem balanced. Supplementing with the best probiotics has been shown to positively influence the gut microbiota, with different strains displaying different effects for the body.

When that balance is off, the impact can go beyond digestion. Bloating, irregularity, low mood and even recurring infections can all be signs that your gut microbiome isn’t functioning as it should, and is often linked to underlying inflammation.

There’s growing evidence to support the gut’s wider role in our health. For instance, one study found that people experiencing low mood tended to have a less diverse gut microbiome, while another study suggested that probiotic, prebiotic and synbiotic supplements may help ease sSupymptoms of anxiety, depression and stress, alongside improving sleep and even supporting conditions like Alzheimer’s disease.

“Our gut microbiome has been linked to the health of pretty much every organ in our body. So gut hormone connection, gut skin connection, gut metabolism connection, all of these different connections,” explains Dr Megan Rossi, a gut health expert with a PhD in probiotics. “Technology has allowed us to understand exactly how powerful our gut microbes are […] our gut health uncovers how we can look better, feel better and live longer, happier lives,” she adds.

It also helps explain why the gut is often described as a ‘second brain.’ Through the gut-brain axis (the communication pathway between your digestive system and brain), imbalances in gut bacteria can influence everything from how you feel to how well you function day to day.

Put simply, these microbes do more than you might think. And while diet should always come first, supplements can offer a useful top-up where needed. With help from the experts, I tested a range of probiotics to see which ones are *actually* worth adding to your routine (and spending on).

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The best probiotics for 2026 are:

  • Best overall – Nutravita 60 billion CFU pro bio cultures complex: £19.99, Amazon.co.uk
  • Best budget buy – Bio-Kult everyday gut, 60 capsules: £20, Boots.com
  • Best for women – Vida Glow gut pro: £24, Spacenk.com
  • Best duo cap – Epetōme: £54.99, Epetome.com
  • Best liquid supplement – Symprove: £49.99, Symprove.com
  • Best multivitamin with a probiotic – You’re Looking Well day pill: £45, Ylwclub.com

How I tested

A selection of probiotics I tested
A selection of probiotics I tested (Emilie Lavinia/The Independent)

I consulted experts (Sophie Medlin and Dr Megan Rossi) to discern what probiotics are, their role within the body, the different strains of bacteria to look out for and the most beneficial doses. I researched a range of probiotics for various needs and tested each one for at least a month and up to three months. I noted any changes to skin health and any stomach issues, and judged each supplement based on its compatibility with a balanced diet. You can read more about my testing criteria at the end of this article.

Read more: Best multivitamins for women, men and children, according to experts

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